2 edition of Epidemiological studies on human rotaviruses. found in the catalog.
Epidemiological studies on human rotaviruses.
Pauline A. Lavigne
Written in English
|The Physical Object|
|Number of Pages||114|
Rotaviruses (RVs) cause life-threatening diarrhea in infants and children worldwide. Recent biochemical and epidemiological studies underscore the importance of histo-blood group antigens (HBGA) as both cell attachment and susceptibility factors for the globally dominant P, P, and . health burden of rotavirus-associated disease is a global public health goal. Human rotaviruses, the major aetiological agents of severeinfantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. Ten VP7 serotypes and 7 VP4 serotypes have so far been detected.
He obtained a Ph.D. in Biomedical sciences in at the University of Leuven. His initial research focuses on the study of complete genomes Dr. Matthijnssens has co-authored more than 85 peer reviewed research papers, and 3 book and genetic diversity of human and animal : Yashpal S. Malik, Jelle Matthijnssens. This study was conducted to determine the incidence of rotavirus infection in children with gastroenteritis attending Jos university teaching hospital, Plateau State. A total of children with acute diarrhea were selected by random sampling. Stool samples were obtained and assayed for rotavirus antigens by enzyme linked immunosorbent assay technique using standard diagnostic BIOLINE Cited by:
An outbreak of enteric disease of unknown etiology with 60% morbidity and 8% mortality in weaning piglets occurred in November on a farm in Buryat Republic, Russia. Metagenomic sequencing revealed the presence of rotavirus B in feces from diseased piglets while no other pathogens were identified. Clinical disease was reproduced in experimentally infected piglets, yielding the 11 RVB Cited by: 3. Rotaviruses, genus Rotavirus and family Reoviridae, cause gastroenteritis in humans ruses A through G are discriminated on the basis of the antigenicity of VP6. Among rotavirus A, G, and P genotypes are defined by genes encoding outer capsid proteins VP7 and VP4, respectively us reports have suggested that RV group A genotypes G1P, G2P, G3P, G4P and Cited by: 9.
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Molecular Epidemiology of Human Rotaviruses in Latin America Chapter. July ; DOI: /_5. In book: Human Virology tool for epidemiological studies demonstrating. molecular epidemiological studies on rotavirus infection causing severe diarrhea in human, animals and poultry Article (PDF Available) in Bangladesh Journal of Veterinary Medicine 9 (2)(– One of the major challenges in epidemiological studies is the rapid evolution of rotaviruses via different mechanisms.
by reassortment between animal and human rotaviruses, makes it. Large-scale surveillance studies conducted during the s by MAb-EIAs uncovered the global distribution of four major VP7 serotypes of human rotaviruses, designated G1–G4 (Woods et al., ). In animal species, completely different serotype specificities were found to predominate, for example, G5 in pigs and serotypes G6 and G10 in : K.
Bányai, V.E. Pitzer. Induced electropherotyping is now an accepted method not only for epidemiological studies but also as a diagnostic tool, with an advantage of its capability to detect non-group-A rotaviruses.
In the modified A technique the ethanol overnight-precipitation was replaced by a rapid precipitation in liquid nitrogen, which takes only 45 min and Cited by: 7. Rotavirus is a genus of double-stranded RNA viruses in the family ruses are the most common cause of diarrhoeal disease among infants and young children.
Nearly every child in the world is infected with a rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe; adults are rarely : Reoviridae.
Human infection has been reported with groups A, B, and C rotaviruses (RVs). Of these, Group A RVs are the most important, being a major cause of severe gastroenteritis (GE). Each year, Group A RVs are estimated to cause approxdeaths worldwide in children less than 5 years (yr) of age, mostly in developing countries (1).Cited by: 1.
The epidemiology of human rotavirus (HRV) in north-east Scotland was investigated between and During this period HRV infections were recorded. The majority (83%) of the infections were in children less than 5 years of age although some Cited by: Epidemiological studies had demonstrated that the G/P combinations most frequently detected were G1P, G3P, G4P, G2P, G9P and G9P.
In China, the most prevalent combination was G1P untilbut it had shifted to G3P by – In our study, G3P was the most common recombinant followed by G1P, which was Cited by: Most molecular epidemiological studies have analyzed rotaviruses by their electropherotype, since this marker is both characteristic and constant for a given virus strain, i.e., rotaviruses from different ammal species including human exhibit distinct by: 1.
Abstract: Rotaviruses (RVs) cause life-threatening diarrhea in infants and children worldwide. Recent biochemical and epidemiological studies underscore the importance of histo-blood group antigens (HBGA) as both cell attachment and susceptibility factors for the globally dominant P, P, and P genotypes of human RVs.
This study was conducted to detect and characterize prevalent human group A rotavirus strains from diarrheic children in Sokoto, Nigeria, by ELISA, monoclonal antibody (Mab) serotyping and Reverse Transcription-Polymerase Chain Reaction (RT-PCR) techniques.
Rotavirus was detected in % of the children. The G-serotypes observed in circulation were G4: 16 (%), G1: 4 (%), G2: 3 (11 Cited by: 2.
Human rotavirus was discovered in and is known to cause diarrheal disease in infants and young children. The severity of rotaviruses is seen among babies 11 months old and younger with the highest mortality seen in Africa, Latin America, and Asia.
Rotavirus infection causes an acute diarrheal disease, although both in developed and developing countries there is a greater incidence of asymptomatic infection than there is of disease (Black et al., a; Champsaur et al., ).
In developing countries, rotavirus diarrhea persists for 10 or. Rotavirus is a double-stranded RNA virus of the family virus is composed of three concentric shells that enclose 11 gene segments. The outermost shell contains two important proteins—VP7, or G-protein, and VP4, or P-protein.
Rotavirus (RV) is the most common cause of severe childhood diarrhea worldwide. Despite Venezuela was among the first developing countries to introduce RV vaccines into their national immunization schedules, RV is still contributing to the burden of diarrhea.
Concerns exist about the selective pressure that RV vaccines could exert on the predominant types and/or emergence of new Cited by: 5.
Despite all progress obtained in relation to environmental sanitation in the last century, the number of cases of diarrheal disease or acute gastroenteritis resulting from consumption of contaminated water supplies and sanitation deficiencies are alarming.
Currently, diarrheal disease still represents the fourth leading cause of death among children under five years old and viruses represent a.
Rotavirus has been identified among the most important causes of infantile diarrhoea, especially in developing countries. The present study was undertaken to determine the occurrence and clinical symptoms of human rotavirus disease among children presenting with varying degree of diarrhoea in selected urban hospitals in Sokoto metropolis, by: 4.
Rotaviruses (RVs) are a major cause of acute viral gastroenteritis in young animals and children worldwide. Immunocompetent adults of different species become resistant to clinical disease due to post-infection immunity, immune system maturation and gut physiological changes.
Of the 9 RV genogroups (A–I), RV A, B, and C (RVA, RVB, and RVC, respectively) are associated with diarrhea in by: Pediatric Annals | Thirty-two years ago, the etiology of most cases of childhood diarrhea was a mystery.
It was then, inthat viral particles with a wheel-like appearance were first observed Cited by:. Sato K, Inaba Y, Shinozaki T, et al. Isolation of human rotavirus in cell cultures: brief report.
Arch Virol ; Wyatt RG, James HD Jr, Pittman AL, et al. Direct isolation in cell culture of human rotaviruses and their characterization into four serotypes. J Clin Microbiol ; RV1 and RV5 exert similar effectiveness against homotypic and heterotypic rotavirus strains.
Persistence of specific strains was not recorded, suggesting vaccine-induced selective pressure did not occur. Expansion of rotavirus surveillance efforts to low-income countries and ongoing surveillance are crucial to identify emergence of new strains and to assess strain-specific vaccine Cited by: Molecular Characterization and Epidemiology of Rotavirus Isolates Obtained from Children with Diarrhoea in Malaysia Med J Malaysia Vol 64 No 3 September Fig.
1: Comparative genome profile of Malaysian Group A rotavirus isolates (Lanes 1 to 18), and reference strains.